Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• cyclically amplify the process of DNA self-assembly. The strategies based on enzymatic tools, on the other hand, are characterized by an extraordinary potential for signal amplification. The main advantages of using enzymes involve: a) the capability of modifying oligonucleotides (e.g., polymerases

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• , encompassing the formation of functional hybrid DNA ensembles through coassembly of organic molecules (SFMs) and short oligonucleotides, is envisioned to overcome the limitations associated with classical DNA nanotechnology to realize practical applications [13]. The various design approaches of DNA self

• -assembly and coassembly that have been utilized to form novel nanostructures with a range of applications, from materials to biomedicine, are covered. The judicious exploitation of canonical and noncanonical base pairing interactions supported by various other noncovalent interactions for the creation of

Patterning of supported gold monolayers via chemical lift-off lithography

• Liane S. Slaughter,
• Kevin M. Cheung,
• Sami Kaappa,
• Huan H. Cao,
• Qing Yang,
• Thomas D. Young,
• Andrew C. Serino,
• Sami Malola,
• Jana M. Olson,
• Stephan Link,
• Hannu Häkkinen,
• Anne M. Andrews and
• Paul S. Weiss

Beilstein J. Nanotechnol. 2017, 8, 2648–2661, doi:10.3762/bjnano.8.265

• -enhanced to visualize the features more clearly. The original images are shown in Figure S2 (Supporting Information File 1). Fluorescence visualization of patterned lifted-off Au–alkanethiolate monolayers via DNA self-assembly and hybridization. (A) (Top) Scheme for complementary DNA hybridization

• . Square regions are dark due to the absence of Au, and therefore, also the absence of self-assembled DNA necessary for hybridization. (B) (Top) Scheme for noncomplementary control experiments. (Bottom) Similar substrate and DNA self-assembly as in panel A with the exception that scrambled

• , noncomplementary, fluorescently labeled DNA was used for hybridization. (C) Flat PDMS was patterned with Au–alkanethiolate monolayers in the “CNSI” lettered and “UCLA” relief regions. The patterns were then visualized using the same DNA self-assembly and hybridization procedure as in panel A. (D) A different

Hierarchical coassembly of DNA–triptycene hybrid molecular building blocks and zinc protoporphyrin IX

• Rina Kumari,
• Sumit Singh,
• Mohan Monisha,
• Sourav Bhowmick,
• Anindya Roy,
• Neeladri Das and
• Prolay Das

Beilstein J. Nanotechnol. 2016, 7, 697–707, doi:10.3762/bjnano.7.62

• therapy (PDT) applications as well as photocatalytic reactions. Keywords: DNA nanostructure; DNA–organic hybrid; DNA self-assembly; 2,6,14-triptycenetripropiolic acid; zinc protoporphyrin IX; Introduction Hybrid nanomaterials resulting from the covalent conjugation of DNA with organic molecules [1][2][3